主要成果 | 基金项目： [1] 针刺手法和参数对针刺效应启动的影响及其机制(82305416), 国家自然科学基金青年项目, 30万, 2024.01-2026.12, 主持. [2] 针刺手法和参数影响得气效果的生物力学机制(23YF1418300), 上海市青年科技扬帆计划, 20万, 2023.04-2026.03, 主持. 发表论文： [1]Yu Y, Wang YX, Qiao X, Li YC, Liu YH, Huang Z, Yao W. Influence of acupuncture twisting parameters on analgesic effects mediated by mast cells in AA rat models. Biomedical Journal. 2025, 100876. [2]Yi Yu#, Jing-Jing Huang#, Hui Yang*, Liu-Jie Ren*. Automated diagnostic method for sleep apnea and hypopnea using overnight airflow and oxygen saturation. MethodsX, 2025, 15: 103528. [3]Yuhang Liu, Mingzhu Sun, Yixuan Wang, Yingchen Li, Ziliang Zhang, Liujie Ren, Wei Yao*, Yi Yu*. Mast cell degranulation mediates analgesic effects of acupuncture at different stimulation durations in arthritic rats. Integrative Medicine Research, 2025, 101196. [4]Wang Yi-Xuan, Liu Yu-Hang, Zhang Xuan, Li Ying-Chen, Ren Liu-Jie, Ding Guang-Hong, Yao Wei, Yu Yi*. Influence of acupuncture intensity on analgesic effects in AA rat models. Frontiers in Bioengineering and Biotechnology, 2024, 12: 1502535. [5]Li Y C, Yi Yu#, Qiao X, et al. A robot arm-assisted acupuncture system with motion and force monitoring: establishment and validation[J]. Frontiers in Bioengineering and Biotechnology, 2025, 13: 1563263. [6]Liu-Jie Ren#, Yi Yu#, Cheng Hua, You-Zhou Xie, Wen-Juan Yao, Jun-Yi Liang*, Chen-Long Li*, Tian-Yu Zhang*. Interference pattern caused by bilateral bone conduction stimulation impairs sound localization. Advanced Science, 2025, e00302. doi: 10.1002/advs.20250302. [7]Li YC#, Yu Y#, Qiao X, Ren LJ, Xu JW, Wang X, Gu W, Yao W. A robot arm-assisted acupuncture system with motion and force monitoring: establishment and validation. Frontiers in Bioengineering and Biotechnology.;13:1563263. [8]Yi Yu, Liu-Jie Ren, Xin-Yue Liu, Xiao-Bo Gong, Wei Yao*. Effects of substrate stiffness on mast cell migration. European Journal of Cell Biology, 2021, 100(7–8): 151178. [9]Yu Y, Yao W, Ding G. A Mathematical Model to Study the Mechanical Information Induced by Lifting-Thrusting Needle. Evidence-Based Complementary and Alternative Medicine. 2019. [10]Yu Y, Shi Y, Yao W. Dynamic model of tuberculosis considering multi-drug resistance and their applications. Infectious Disease Modelling. 2018 Jan 1;3:362-72. [11]Liu-Jie Ren#, Yi Yu#, Yu-Heng Zhang, Xin-D Liu, Zeng-Jun Sun, Wen-Juan Yao, Tian-Yu Zhang, Cheng Wang*, Chen-Long Li*. Three-dimensional finite element analysis on cochlear implantation electrode insertion. Biomechanics and Modeling in Mechanobiology. 2022, 22:467-478. [12]Yao W, Yu Y, Ding G. A hybrid method to study the mechanical information induced by needle rotating. Mathematical Methods in the Applied Sciences. 2018;41(15):5939-50. [13]Li Y, Yu Y, Liu Y, Yao W. Mast cells and acupuncture analgesia. Cells. 2022 Mar 2;11(5):860. [14]Ren LJ, Yu Y, Fang YQ, Hua C, Dai PD, Zhang TY. Finite element simulation of cochlear traveling wave under air and bone conduction hearing. Biomechanics and Modeling in Mechanobiology. 2021 Aug;20(4):1251-65. [15]Liu X, Tsubota KC, Yu Y, Xi W, Gong X. A numerical method to predict the membrane tension distribution of spreading cells based on the reconstruction of focal adhesions. Science China Physics, Mechanics & Astronomy. 2022 Jun;65(6):264612. [16]Yao W, Shen Z, Yu Y, Ding G. Mechanical effects of acupuncture. Mathematical Methods in the Applied Sciences. 2020 Mar 15;43(4):1555-64. [17]Sun MZ, Wang X, Li YC, Liu YH, Yu Y, Ren LJ, Gu W, Yao W. Effects of acupuncture needle modification on acupuncture analgesia. Journal of Integrative Medicine. 2025 Jan 1;23(1):66-78. [18]于仪, 王心玥, 吕杰, 张天宇, 任柳杰. 鼓室硬化对中耳传声影响的有限元分析[J]. 听力学及言语疾病杂志, 2025, 33(1): 34-39. [19]刘宇航, 于仪, 王译萱, 姚伟. 针刺时长与针刺镇痛效果的相关性分析[J]. 复旦学报（自然科学版）, 2025, 64(2): 0427-7104(2025)02-0140-08. [20]张子良, 于仪, 乔璇, 陈恩纳, 徐靖雯, 姚伟. 手针通过肥大细胞脱颗粒产生镇痛效果的动物实验研究[J]. 医用生物力学, 2025.
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